Dear Hair Restoration Physician,

     

Figures 1, 2 – Calculated Dose of Photo-Energy Per Treatment (Joules/cm^2) of  common photomedicine devices for hair regrowth, all in the red-light spectrum;  Figure 2 shows energy calculations

This is a follow up to last week’s FUE-Europe 2019 lecture discussion on platelet lysate, prp growth factor concentration and the need to set up a bench process to quantify associated hair growth effects (i.e.,  wet lab for culture of hair follicles to grow hair in vitro; see  Philpot 2018     Raposio 2016).

At the same time, we should study photo-energy’s direct effect on in vitro follicle hair production (length change and/or thickness by long, short axis diameter changes)  along with indirect effect by irradiation of prp culture media prior to its use (i.e., will photostim of prp prep with associated increased atp production in platelet mitochondria lead to increased growth factors, etc.).

Photo-energy biologic effects are generally dose-dependent.  The above figures show some common photomedicine devices for hair regrowth, all in the red-light spectrum, with their associated treatment doses (Joules/cm^2).   Photo-energy treatment dose (power x time) is the 1st parameter we will study at the bench to reproduce and build on a recent Korean in-vitro hair follicle study that demonstrated this dose dependency; see rx.lasercap.us.

In the meanwhile, I encourage you to use photomedicine for hair regrowth ROUTINELY in the medical management of your hair loss patients, as their are numerous references in the literature supporting efficacy for hair regrowth (see relevant pubmed references);  and LaserCap Company will continue to work diligently to more clearly define optimal dose parameters.

Cheers

Mike

Ps our PRP Cell Lab which has been set up as part of our ‘prp + photomed for hair regrowth’ registry trial planning, is open to perform cell counts with differentials on your PRP preparations – e.g., we can perform the same set of whole blood and prp cell counts with differentials as this $2000/prp-certification private lab, at no cost to physicians who purchase LaserCap® devices for use with their patients, and we include microscopic exam (see prp.lasercap.us; clinical relevance of microscopic to be determined, however it is an interesting visual of the prp prep). 

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